Biomass Group, Nanjing Agricultural University, PO Box 68, 40 Dianjiangtai Road, Nanjing 210031

A green process for biodiesel and hydrogen coproduction from waste oils with a magnetic metal-organic framework derived material

Recently, Dr. Wen-jie Cong (female) supervised by Prof. Zhen Fang published a research article in Biomass & Bioenergy about biodiesel and hydrogen coproduction from waste oils with a solid base derived from magnetic metal-organic framework.

Magnetic self-assembly metal-organic frameworks (MOFs) were constructed for the co-production of biodiesel and hydrogen from waste oils. The highly active MOF nanoparticles were synthesized and catalyzed crude glycerol for 126.8% hydrogen yield in subcritical water (350 ℃, 5 min). By coupling alkali with MOF-derived carriers, continuous process of fast production of biodiesel (with microwave heating at 90 ℃ in 15 min, 15:1 methanol/oil molar ratio and 9 wt.% catalyst dosage) and hydrogen (350 ℃, 5 min) were achieved with yield of 95.3% biodiesel from waste oil (AV was 3.95 mg KOH) and 102.6% H2 from crude glycerol by-product, respectively. The nanoparticles were magnetically separated for 5 cycles with 95% biodiesel yield and increased hydrogen yield by 50% after deactivated. Characterization techniques showed active sites of MOF-derived nanoparticles were well dispersed with surface area increased by 3.9 times for highly efficient production of biodiesel and hydrogen. It revealed that MOF materials can be designed to make active catalysts and carriers for loading catalytic sites for biomass conversions to targeted biofuels.

A self-assembled nano Ni-MOF was synthesized as magnetic carrier and catalyst support for biodiesel and hydrothermal hydrogen production from waste oils. (以自组装纳米Ni-MOF作为磁性载体制备催化剂，以废弃油脂为原料联合生产生物柴油和氢气）

Related results were accepted in Biomass & Bioenergy:

WJ Cong, J Yang, JG Zhang, Zhen Fang^*, ZD Miao. A green process for biodiesel and hydrogen coproduction from waste oils with a magnetic metal-organic framework derived material. Biomass & Bioenergy. 175 (2023) 106871. https://doi.org/10.1016/j.biombioe.2023.106871.

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磁性金属有机骨架衍生材料用于废油联产生物柴油和氢气的绿色工艺

最近，丛文杰博士（女）在方老师的指导下，在国际学术期刊Biomass & Bioenergy（IF5.77，Q1）发表金属有机框架衍生固体碱联合制备生物柴油和氢气的研究性论文。

本研究通过制备自组装磁性纳米金属有机骨架 (Ni-MOF)，构建了以废弃油为原料联合制备生物柴油和氢气的绿色工艺。在亚临界水（350 ℃，5 min）条件下，该高活性Ni-MOF纳米颗粒催化粗甘油水热制氢，氢气产率高达126.8%。以该Ni-MOF为载体制备磁性固体碱，实现高酸值废弃油（酸值3.95 mg KOH）制备生物柴油，产率为95.3%（90 ℃、15 min、甲醇/油摩尔比15:1、催化剂用量为9 wt.%），该磁性固体碱经磁性分离后重复使用5次，生物柴油产率为95%；失活后的磁性固体碱用于水热气化副产物粗甘油制备氢气，产率为102.6%（350 ℃，5 min），氢气产率提高了50%。研究结果表明该Ni-MOF纳米颗粒活性位点分散性好，比表面积增加了3.9倍，可高效联产生物柴油和氢气。该MOF材料可以设计成多功能磁性载体和高性能催化剂，用于负载高活性催化位点实现生物质快速转化为生物燃料。

详情可见：

WJ Cong, J Yang, JG Zhang, Zhen Fang^*, ZD Miao. A green process for biodiesel and hydrogen coproduction from waste oils with a magnetic metal-organic framework derived material. Biomass & Bioenergy. 175 (2023) 106871. https://doi.org/10.1016/j.biombioe.2023.106871.

Efficient lipid synthesis of Chlorella pyrenoidosa promoted under heavy metals from electric arc furnace slag

Recently, Dr Yi-Tong Wang (female, Associate Professor, College of Metallurgy and Energy, North China University of Science and Technology) and Prof. Zhen Fang published an article in Journal of Cleaner Production (IF: 11.072, Q1) about using efficient lipid synthesis of Chlorella pyrenoidosa microalgae promoted under heavy metals from electric arc furnace slag.

Electric arc furnace slag is highly productive and rich in elements, which can be used as a nutrient source for microalgae. The study investigated the regulation of growth and lipid synthesis of Chlorella pyrenoidosa in electric arc furnace slag leaching solution, and citric acid electric arc furnace slag co-leaching solution, to achieve lipid production while treating metallurgical solid waste. The results showed that the highest biomass and lipid contents were 0.23 g/L and 45.89 wt%, respectively, when BG11 was added to the electric arc furnace slag leaching solution. The highest biomass and lipid contents were 0.25 g/L and 33.37 wt%, respectively, for the addition of citric acid electric arc furnace slag leaching solution at BG11. Various metal ions in the electric arc furnace slag leaching solution increased the biomass lipid content by modulating acetyl-CoA carboxylase, malic enzyme, and phosphoenolpyruvate carboxylase activities. This study helps to solve the problem of the high cost of microalgae culture and metallurgical solid waste treatment while generating lipids and provides a new green pathway for the commercialization of microalgae.

Related results were accepted in Journal of Cleaner Production:

Q Yu, TJ Liu, YN Zeng, YT Wang*, JG Li*, LL Kang, R Ji, FP Wang, XM Wang, B Liu, S Cai, Zhen Fang*. Efficient lipid synthesis of Chlorella pyrenoidosa promoted under heavy metals from electric arc furnace slag. Journal of Cleaner Production, 2023, 414, 137648. https://doi.org/10.1016/j.jclepro.2023.137648

High lipid content (45.89 wt%) was obtained by adding EAFS leaching solution into BG11. High biomass content (0.44 g/L) was achieved by citric acid assisting EAFS leaching. 在BG11中加入EAFS浸出液，获得了较高的脂质含量(45.89 wt%)。柠檬酸辅助EAFS浸出可获得较高的生物质含量(0.44 g/L)。

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电炉渣重金属胁迫促进Chlorella pyrenoidosa微藻高效合成油脂

最近，青年女科学家王一同博士（华北理工大学冶金与能源学院副教授）和方真教授在国际学术期刊Journal of Cleaner Production（IF: 11.072，Q1）发表题为“电炉渣重金属胁迫促进Chlorella pyrenoidosa高效合成脂质”的研究性论文。

电炉渣产量高，元素丰富，可作为微藻的营养来源。研究了Chlorella pyrenoidosa在电炉渣浸出液和柠檬酸电炉渣共浸出液中的生长和脂质合成的调节机制，实现冶金固体废物资源化同时获得高附加值脂质。结果表明，当在BG11添加电炉渣浸出液中时，生物量和脂质的最高含量分别为0.23g/L和45.89wt%。在BG11添加柠檬酸电炉渣联合浸出液时，生物量和脂质含量分别为0.25g/L和33.37wt%。电炉渣浸出液中的各种金属离子通过调节乙酰辅酶A羧化酶、苹果酸酶和磷酸烯醇丙酮酸羧化酶的活性来增加脂质含量。本研究有助于解决微藻培养和冶金固废处理成本高的问题，为微藻商业化提供新思路。详情可见：

Q Yu, TJ Liu, YN Zeng, YT Wang*, JG Li*, LL Kang, R Ji, FP Wang, XM Wang, B Liu, S Cai, Zhen Fang*. Efficient lipid synthesis of Chlorella pyrenoidosa promoted under heavy metals from electric arc furnace slag. Journal of Cleaner Production, 2023, 414, 137648. https://doi.org/10.1016/j.jclepro.2023.137648

Miss Xiao-le Liu and Mr. Jian Yang successfully defended their Doctoral and Master theses

On May 26, 2023, Miss Xiao-le Liu and Mr. Jian Yang, supervised by Prof. Zhen Fang, successfully defended their theses at C302 Yuxian Building, Pukou Campus of Nanjing Agricultural University. The defending committee was composed of Prof. Mao-hua Xiao (Chair) from Nanjing Agricultural University, Profs Wei Zhuang and Jun Zhou from Nanjing Tech University as well as Profs Chang-ying Ji, Wei-min Ding and Chun-xia He from Nanjing Agricultural University (NJAU).

Miss Liu and Mr. Yang presented their research results for doctoral and master theses, the committee members raised relevant questions. Based on the replies and theses reviewed, the panels agreed that Miss Liu and Mr. Yang had successfully completed their research and course requirements in agricultural bio-environment and energy engineering. Miss Liu studied the production of microbial lipid from wheat straw with dissertation entitled “Study on mechanochemical pretreatment of wheat straw and enzymatic hydrolysate for microbial lipid production”. She significantly improved the enzymatic hydrolysis efficiency of wheat straw pretreated by solid particle-assisted ball milling pretreatment, and realized the efficient production of lipid from the enzymatic hydrolysis of pretreated wheat straw. Mr. Yang studied biodiesel production of waste cooking oil by bifunctional magnetic catalysts with his thesis entitled “Microwave Assisted Production of Biodiesel from Waste Cooking Oil by Bifunctional SrO-ZnO/MOF Catalyst”. Miss Liu published 2 academic papers and Mr. Yang published 1 academic papers. Both of them had all been awarded the title of “Outstanding Graduate of NJAU”. Mr. Yang won President Scholarship of NJAU.

After the juries voted by secret ballot, the panels agreed to confer Doctor of Philosophy in Engineering to Miss Xiao-Le Liu, and Master of Engineering degree to Mr. Yang Jian, subjected to the approval by the Academic Degrees Committees of the college and university.

 

Congratulations to Miss Liu and Mr. Yang!

Papers published:

XL Liu, Zhen Fang*, XF Tian*, ZD Miao, Impact of Alkalic Salt Coupled Ball Milling Pretreatment of Wheat Straw on Improving Enzymatic Hydrolysis and Energy Efficiency, Fuel, 340 (2023), 127336. https://doi.org/10.1016/j.fuel.2022.127336.

XL Liu, CY Dong, SY Leu, Zhen Fang*, ZD Miao, Efficient Saccharification of Wheat Straw Pretreated by Solid Particle-Assisted Ball Milling with Waste Washing Liquor Recycling, Bioresource Technology, 347 (2022), 126721. https://doi.org/10.1016/j.biortech.2022.126721.

Jian Yang, Wen-Jie Cong, Zongyuan Zhu**, Zheng-diao Miao, Yi-Tong Wang***, Michael Nelles, Zhen Fang*. Microwave-assisted one-step production of biodiesel from waste cooking oil by magnetic bifunctional SrO–ZnO/MOF catalyst. Journal of Cleaner Production, 395 (2023) 136182. https://doi.org/10.1016/j.jclepro.2023.136182.

刘小乐和杨剑同志顺利通过博士和硕士论文答辩

 

2023年5月26日上午，南京农业大学生物能源组2019级博士研究生刘小乐（女）和硕士生杨剑（导师方真教授）毕业答辩会在南京农业大学浦口校区育贤楼C302举行。南京农业大学的肖茂华教授担任答辩评审委员会主席，南京工业大学的庄伟教授和周俊教授，南京农业大学的丁为民，姬长英教授和何春霞教授共五位专家担任评审委员。

答辩会上，刘小乐同学和杨剑同学对其在校期间的学术论文进行汇报，同时答辩委员会主席和各位评委提出了相关问题。根据刘小乐同学和杨剑同学的问题回答以及学位论文的评阅，评委会经过评审决议，一致认为刘小乐同学和杨剑同学顺利完成了农业生物环境与能源方面的研究和学习要求。刘小乐同学在毕业论文《机械化学法预处理小麦秸秆及其酶解液发酵产微生物油脂的研究》中研究了球磨和化学颗粒结合预处理小麦秸秆，实现了小麦秸秆的结构解聚，有效提高了小麦秸秆在较低酶载量和较短时间内的酶水解效率，并将水解获得的可发酵性碳源用于发酵产微生物油脂，实现了农作物秸秆到微生物油脂的资源化利用。杨剑同学在毕业论文《双功能SrO-ZnO/MOF催化剂微波辅助餐厨废油制备生物柴油》中研究了利用双功能磁性催化剂催化废油脂制备生物柴油，实现了在较温和条件下一步法催化高酸值废弃油制备生物柴油。刘小乐同学以第一作者身份共发表学术论文2篇，杨剑同学以第一作者发表学术论文1篇，两人均获得2023南京农业大学优秀毕业生称号。杨剑同学获得南京农业大学校长奖学金。

经评委会无记名投票表决，一致同意刘小乐同学通过博士学位论文答辩，建议授予工学博士学位；杨剑同学通过硕士学位论文答辩，建议授予杨剑工学硕士学位。

 祝贺刘小乐和杨剑同学！

发表的论文：

XL Liu, Zhen Fang*, XF Tian*, ZD Miao, Impact of Alkalic Salt Coupled Ball Milling Pretreatment of Wheat Straw on Improving Enzymatic Hydrolysis and Energy Efficiency, Fuel, 340 (2023), 127336. https://doi.org/10.1016/j.fuel.2022.127336.

XL Liu, CY Dong, SY Leu, Zhen Fang*, ZD Miao, Efficient Saccharification of Wheat Straw Pretreated by Solid Particle-Assisted Ball Milling with Waste Washing Liquor Recycling, Bioresource Technology, 347 (2022), 126721. https://doi.org/10.1016/j.biortech.2022.126721.

Jian Yang, Wen-Jie Cong, Zongyuan Zhu**, Zheng-diao Miao, Yi-Tong Wang***, Michael Nelles, Zhen Fang*. Microwave-assisted one-step production of biodiesel from waste cooking oil by magnetic bifunctional SrO–ZnO/MOF catalyst. Journal of Cleaner Production, 395 (2023) 136182. https://doi.org/10.1016/j.jclepro.2023.136182.

 

国际农林生物质利用研讨会(BUAF2022)成功举办

发展低碳技术、可再生能源及可持续发展策略是实现联合国可持续发展目标(Sustainable Development Goals, SDGs)的重要手段。农林生物质利用已成为农业、环境、能源、材料等领域研究热点。2022年12月15日-16日，国际农林生物质利用研讨会(BUAF2022)在线上隆重召开。

本次研讨会(BUAF2022)由南京农业大学主办，南京农业大学方真教授为大会主席，主题为“生物质利用助推可持续发展”。15位来自比利时、加拿大、德国、日本、马来西亚、美国、西班牙和中国的世界知名学者【6位国内外院士（包括大会主席）、2位美国会士、1位国家友谊奖获得者】汇聚一堂分享其在生物质利用领域的最新研究进展。意大利都灵大学Giancarlo Cravotto教授；比利时根特大学Kevin M Van Geem教授；中国科学院院士、Green Chemistry副主编、中国科学院化学研究所韩布兴教授；加拿大工程院院士、加拿大化工学会主席、多伦多大学Charles Q Jia教授；日本东北大学Richard L Smith, Jr教授；加拿大工程院院士、湖首大学工学院院长Janusz A Kozinski教授；德国霍恩海姆大学Dr habil, Andrea Kruse教授；西班牙科尔多瓦大学Rafael Luque教授；日本广岛大学Yukihiko Matsumura教授；国家友谊奖获得者、德国生物质研究中心科学主任、德国罗斯托克大学Dr mont Michael Nelles教授；美国农业和生物工程学会会士、明尼苏达大学Roger Ruan教授；加拿大工程院院士、西安大略大学Charles Xu教授；马来西亚国民大学Sarani Zakaria教授；美国农业与生物工程学会会士、加利福尼亚大学戴维斯分校Ruihong Zhang教授；中国科学院院士、中国科学院副院长张涛教授分享其在生物质能源、生物基材料、生物基化学品和地球碳平衡等相关领域的最新研究成果。会议旨在增进世界各国学者在生物质利用与可持续发展研究方面的国际学术交流与合作。

演讲录像：

Part 1 (Dec 15, morning)：

https://www.bilibili.com/video/BV1Lv4y167Ec/?vd_source=af4c328789c00807658eade9c65b9baa

Part 2 (Dec 15, afternoon)：

https://www.bilibili.com/video/BV1o3411S7iR/?vd_source=af4c328789c0080

Part 3 (Dec 16, morning)：

https://www.bilibili.com/video/BV1k8411J7kE/?vd_source=af4c328789c00807658eade9c65b9baa

Part 4 (Dec 16, afternoon)：

https://www.bilibili.com/video/BV1HK411i7rH/

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Int’l Symp. on Biomass Utilization in Agriculture and Forestry (BUAF2022)

The International Symposium on Biomass Utilization in Agriculture and Forestry (BUAF2022, Virtual Conference) was successfully held on December 15-16, 2022 and hosted by Nanjing Agricultural University and Jiangsu Foreign Expert Lab. Fifteen Scholars from Belgium, Canada, Germany, Italy, Japan, Malaysia, USA, Spain and China shared their most recent research activities on biomass energy, bio-based materials, bio-based chemicals, bio-active compounds and biopolymers, and global carbon balance. The purpose is to promote international academic exchange and education and to stimulate cooperative activities in sustainable development of renewable biomass resources.

Organization Committee

Chair: Professor Zhen Fang (Fellow of the Canadian Academy of Engineering, FCAE), Nanjing Agricultural University, China

Co-chairs: Professor Janusz A. Kozinski (FCAE), Lakehead University, Canada

Professor Richard L Smith, Jr, Tohoku University, Japan

Professor Charles Xu (FCAE), Western University, Canada

Secretaries: Dr Chengyu Dong (Email: dongchengyu@njau.edu.cn, c: 15011223564)

Ms Jing-mei Chen (Email: chenjingmei@njau.edu.cn, c: 13776504416 )

Assistants: Mr Guo-qiang Zhu, Miss Wan-ying Qiu, Dr Yan Yu (The University of British Columbia), Mr Chun Fang (New York University)

URLs:

https://woodrefinery.com/zhenfang/buaf2022-symp/

https://biomass-group.njau.edu.cn/info/1016/1882.htm

Videos:

Bilibili:

Part 1 (Dec 15, morning)：

https://www.bilibili.com/video/BV1Lv4y167Ec/?vd_source=af4c328789c00807658eade9c65b9baa

Part 2 (Dec 15, afternoon)：

https://www.bilibili.com/video/BV1o3411S7iR/?vd_source=af4c328789c0080

Part 3 (Dec 16, morning)：

https://www.bilibili.com/video/BV1k8411J7kE/?vd_source=af4c328789c00807658eade9c65b9baa

Part 4 (Dec 16, afternoon)：

https://www.bilibili.com/video/BV1HK411i7rH/

Youtube:

Part 1 (Dec 15, morning)：

https://www.youtube.com/watch?v=p4kWzlYNOsc

Part 2 (Dec 15, afternoon)

https://www.youtube.com/watch?v=4pMRVWz20a4

Part 3 (Dec 16, morning)：

https://www.youtube.com/watch?v=voNVJday0Ek

Part 4 (Dec 16, afternoon)：

https://www.youtube.com/watch?v=dPzP8AE5mac

Lectures

1.Enabling Technologies for Biomass Extraction and Conversion

Professor Giancarlo Cravotto

Editor-in-Chief of Processes, University of Turin, Italy

2.Gaining Fundamental Understanding of Biomass Fast Pyrolysis by Advanced Experimentation, Genetic Modifications and Kinetic Modeling

Professor Kevin M Van Geem

Ghent University, Belgium

3.Conversion of Biomass into Chemicals and Fuels

Professor Buxing Han

Academician of Chinese Academy of Sciences, Institute of Chemistry

Chinese Academy of Sciences (CAS), China

4.Monolithic Wood Biochar as Functional Material for Sustainability

Professor Charles Q Jia

Fellow of the Canadian Academy of Engineering

Department of Chemical Engineering and Applied Chemistry

University of Toronto, Canada

5.Green Chemical Processes for Upgrading Biomass and Agricultural Wastes

Professor Richard L Smith, Jr

Graduate School of Environmental Studies (GSES)/GP-RSS

Tohoku University, Japan.

6.Biofuture: Exotic Combustion in Supercritical Water

Professor Janusz A Kozinski

Fellow of the Canadian Academy of Engineering, Dean of Engineering, Lakehead University, Canada

7.The Hohenheim on-Farm Biorefinery

Professor Dr habil, Andrea Kruse

University of Hohenheim, Germany

8.Biomass Valorisation into High-added Value Products: from Energy Vectors to Pharmaceuticals

Professor Rafael Luque

Editor in Chief of Molecular Catalysis, University of Cordoba, Spain

9.Hiroshima Scenario: Possibility of Biomass as Carbon Source and Contribution of Agriculture for Carbon Neutral Society

Professor Yukihiko Matsumura

Hiroshima University, Japan

10.Recovery of Organic Waste and Residues (in Germany) – The Role in Waste Management, Energy System, Bioeconomy and Climate Protection

Professor Dr mont Michael Nelles

University of Rostock Scientific Director of the German Biomass Research Center (DBFZ), Germany

11.Sustainable Agricultural Solid and Liquid Waste Utilization for Circular and Sustainable Economy Development

Professor Roger Ruan

Fellow of American Society of Agricultural and Biological Engineers

University of Minnesota, USA

12.Re-engineering Natural Wood into High Strength Lightweight Bio-composite Material for Structural Application

Professor Charles Xu

Fellow of the Canadian Academy of Engineering

Western University, Canada

13.Effect of Hybridization of Inorganic/Organic Acid as the Liquefaction Catalyst on the Properties of Liquefied Kenaf Polyols

Professor Sarani Zakaria

Department of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (National University of Malaysia), Malaysia

14.Transforming Food and Agricultural Waste into Bioenergy and Bioproducts

Professor Ruihong Zhang

Fellow of American Society of Agricultural and Biological Engineers

University of California, Davis, USA

15.Biomass conversion to ethylene glycol: from fundamental research to industrial application

Professor Tao Zhang

Vice-President and Academician of Chinese Academy of Sciences

Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences, China

Conference Photos

Vice-president Professor Feng Hu (middle-right), Dean Professor Hua Li (right) and Professor Zhen Fang (middle-left), Nanjing Agricultural University

Chair of BUAF 2022, Professor Zhen Fang, Nanjing Agricultural University

Vice-president Professor Tao Zhang, Chinese Academy of Sciences

Professor Janusz A Kozinski (Lakehead University, Canada), host of Dec15 morning section (top-right)

Professor Buxing Han, Chinese Academy of Sciences (bottom-left)

Professor Roger Ruan, University of Minnesota (USA, bottom-middle)

Professor Richard L Smith, Jr (Tohoku University, Japan), host of Dec15 afternoon section (bottom-left) , Professor Dr mont Michael Nelles, University of Rostock (Germany, top-right)

Professor Giancarlo Cravotto, University of Turin (Italy, bottom-left)

Professor Yukihiko Matsumura, Hiroshima University (Japan, top-middle), Professor Kevin M Van Geem, Ghent University (Belgium, top-right)

Professor Sarani Zakaria, the National University of Malaysia (Malaysia, bottom-left)

Professor Charles Xu, (Western University, Canada) host of Dec16 morning section (bottom-right) , Professor Charles Q Jia, University of Toronto (Canada)

Professor Ruihong Zhang, University of California, Davis (USA)

Professor Rafael Luque, University of Cordoba (Spain, bottom-left), Professor Dr habil, Andrea Kruse, University of Hohenheim (Germany, top-right)

Details see:

https://biomass-group.njau.edu.cn/system/resource/pdfjs/viewer.html?file=%2F__local%2FB%2FFB%2FC3%2F3EA92B086C2F15CF01B7A45E057_449FA519_17A3C7C.pdf#page=31&zoom=auto,-15,572

Stabilization of Global and Chinese rice bowl with disruptive technology

As invited by Prof. Zhen Fang, on April 15^th，Prof. Yi-hang Zhang, Director of the Center for in Vitro Synthetic Biology of Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences (CAS), gave an academic lecture at 10 am in C502 conference room of Yixian Building, with the theme of “Agricultural Industrialization+”: Stabilization of global rice bowl with disruptive technology.

Prof. Zhen Fang welcomed the arrival of Prof. Zhang and briefly introduced Prof. Zhang.

Prof. Zhang thanked Prof. Zhen Fang’s invitation to give a lecture on the “two paths and one goal” (straw to starch production and CO₂ production of food for the goal of the strategic needs of national food security) as well as reaching the national carbon goals, guaranteeing people’s health and maintaining rural revitalization to meet the UN sustainable development goals (SDGs). Professor Zhang said that it is necessary to lead the development of a full set of independent and self-improvement new biological refining technologies for producing starch, protein and healthy sugars from straw, the main components of artificial food, and developing straw grain synthesis technologies that are economic viable in 3-5 years. In addition, Professor Zhang also showed that innovative energy-driven material synthesis models will solve the problem of low energy efficiency and slow conversion rate of natural photosynthesis, and it is expected that CO₂ production of artificial food could be industrialized in 2036.

Professor Yi-Heng Zhang Bio, Bachelor and Master degrees in Bioengineering, East China University of Science and Technology, Ph.D. in Chemical Engineering, Dartmouth. Professor (level 2) of Tianjin Institute of Industrial Biotechnology, CAS. He is director of the National Key Laboratory of Low-carbon Synthetic Engineering Biology, director of the Center for in Vitro Synthetic Biology of Tianjin Institute, doctoral supervisor. He is “One Hundred Program Scholar” (class A) of CAS, one of the world’s most-recognized pioneers in vitro synthetic biology who proposed the design principle of in vitro multi-enzyme molecular machines for the first time. He developed the electricity-hydrogen-sugar (secondary energy) cycle theory that systematically solves the problems of electricity storage, hydrogen production, storage and transportation, and realizes the production of high-quality hydrogen energy at ambient conditions for the first time. He developed a full set of independent self-reliant industrialization technologies for the “new biorefinery plant” for producing artificial food, and led the starch-to-inositol (vitamin B8) project, the world’s first industrial demonstration of in vitro synthetic biotechnology, and pioneered a new method for inositol biomanufacturing.

秸秆直接酶转化为淀粉、蛋白和健康糖等人造粮食

2023年4月15日，应方真教授邀请，中科院天津工业生物技术所体外合成生物学中心主任张以恒教授于上午10点在育贤楼C502会议室为生物能源组和研究生做学术讲座，主题为“农业工业化+”：用颠覆性技术端稳中国饭碗为主题。

方真教授对张以恒教授的到来表示欢迎并简要介绍了张以恒教授。

张以恒教授感谢方真教授的邀请，围绕“两个路径一个目标”展开演讲，两个路径指秸秆制粮和CO₂生产粮食，一个目标满足国家粮食安全、双碳目标、关注人民健康和乡村振兴的战略需求。张以恒教授表示，要领导发展全套自主自强新生物炼制技术-秸秆直接酶转化为淀粉、蛋白和健康糖等人造粮食，在3-5年内开发用得上、用得起、用的好的秸秆制粮技术。并且，张以恒教授还表明，将创新能量驱动物质合成模式，解决自然光合作用能量效率低、转换速度慢的问题，预计在2036年将CO₂生产粮食产业化。

张以恒教授, 华东理工大学生物工程学士和硕士、美国达特茅斯学院化学工程博士。中科院天津工业生物技术研究所二级研究员，低碳合成工程生物学全国重点实验室主任，天津所体外合成生物学中心主任，博士生导师，中科院百人计划A类—学术帅才，全世界公认的体外合成生物学奠基人之一，首次提出体外多酶分子机器设计原理。他提出的电-氢-糖（二次能源）循环理论系统性解决电储存、氢产储运的难题，第一次实现从环境热量生产高品质氢能。他开发以生产人造粮食为目的的“新生物炼制工厂”的全套自主自强工业化技术，所领导的淀粉制肌醇（维生素B8）项目是全球首个体外合成生物技术的工业化示范，首创肌醇生物制造新方法。