{"id":6434,"date":"2026-06-08T10:54:31","date_gmt":"2026-06-08T02:54:31","guid":{"rendered":"https:\/\/woodrefinery.com\/zhenfang\/?p=6434"},"modified":"2026-06-08T10:54:31","modified_gmt":"2026-06-08T02:54:31","slug":"%e7%90%83%e7%a3%a8%e8%be%85%e5%8a%a9des%e9%a2%84%e5%a4%84%e7%90%86simultaneous-production-of-high-concentration-sugar-and-purity-lignin-from-wheat-straw-via-ball-milling-assisted-des-pretreatment-for","status":"publish","type":"post","link":"https:\/\/woodrefinery.com\/zhenfang\/%e7%90%83%e7%a3%a8%e8%be%85%e5%8a%a9des%e9%a2%84%e5%a4%84%e7%90%86simultaneous-production-of-high-concentration-sugar-and-purity-lignin-from-wheat-straw-via-ball-milling-assisted-des-pretreatment-for\/","title":{"rendered":"\u7403\u78e8\u8f85\u52a9DES\u9884\u5904\u7406Simultaneous production of high-concentration sugar and purity lignin from wheat straw via ball-milling assisted DES pretreatment for high-loading enzymatic hydrolysis"},"content":{"rendered":"

Simultaneous production of high-concentration sugar and purity lignin from wheat straw via ball-milling assisted DES pretreatment for high-loading enzymatic hydrolysis<\/strong><\/p>\n

\u00a0<\/strong>Recently, PhD student Miss Li Wang supervised by Prof. <\/strong>Zhen Fang, <\/strong>collaborated with Prof Roger Ruan (Minnesota Univ, USA)<\/strong>\uff0c<\/strong> p<\/strong>ublished a research paper in the international academic journal Biomass and Bioenergy <\/em>(Q1; Impact factor: 5.8) on the simultaneous production of high-concentration sugar and purity lignin from wheat straw.<\/p>\n

A green pretreatment strategy using ball-milling assisted deep eutectic solvent (composed of choline chloride, ethylene glycol, and oxalic acid) on wheat straw was developed. Under optimized pretreatment conditions (110 \u25e6C, 1:10 (m\/v), 2.5 h), 82% lignin and 99% hemicellulose were removed. Glucose concentration reached 220 g\/L after 120 h of enzymatic hydrolysis with 10 FPU\/g cellulase and 2.5% PEG 6000, which was 7.3% higher than the result obtained without PEG 6000. This is one of the highest glucose concentrations reported for fed-batch enzymatic hydrolysis at such low enzyme loading (10 FPU\/g). This high glucose concentration resulted from substrate modifications (reduced hydrophobicity, enhanced specific surface area, and exposure of more reducing ends) that created optimal attack sites for cellulase. The fed-batch strategy further improved hydrolysis efficiency by increasing free water and restricting cellulase adsorption by lignin. Meanwhile, lignin with high purity (97.6%) and uniform molecular weight was obtained. Unlike most existing pretreatment strategies that prioritize either sugar yield or lignin quality, this study achieved the co-production of high-concentration sugar and high-purity lignin, thereby advancing a sustainable biorefinery for lignocellulose valorization. Related results were published in Biomass and Bioenergy\uff1a<\/p>\n

L Wang, J-Y Chen, Y Cao, Roger, Ruan, Zhen Fang*<\/strong>, Simultaneous production of high-concentration sugar and purity lignin from wheat straw via ball-milling assisted DES pretreatment for high-loading enzymatic hydrolysis. Biomass and Bioenergy 2026, 215, 109655. https:\/\/doi.org\/10.1016\/j.biombioe.2026.109655<\/a>.<\/p>\n

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Ball-milling assisted deep eutectic solvent achieved high glucose titer with low enzyme dosage and high purity with uniform molecular weight lignin from wheat straw (<\/strong>\u7403\u78e8\u8f85\u52a9<\/strong>DES<\/strong>\u9884\u5904\u7406\u5c0f\u9ea6\u79f8\u79c6\u8054\u4ea7\u9ad8\u6d53\u5ea6\u7cd6\u4e0e\u9ad8\u7eaf\u5ea6\u6728\u8d28\u7d20<\/strong>)<\/strong><\/p>\n

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\u7403\u78e8\u8f85\u52a9<\/strong>DES<\/strong>\u9884\u5904\u7406\u5c0f\u9ea6\u79f8\u79c6\u8054\u4ea7\u9ad8\u6d53\u5ea6\u7cd6\u4e0e\u9ad8\u7eaf\u5ea6\u6728\u8d28\u7d20<\/strong><\/p>\n

\u6700\u8fd1\uff0c\u535a\u58eb\u751f\u738b\u8389\uff08\u5973\uff09\u5728\u65b9\u771f\u6559\u6388<\/strong>\u7684\u6307\u5bfc\u4e0b\uff0c\u4e0e\u7f8e\u56fd\u660e\u5c3c\u82cf\u8fbe\u5927\u5b66\u962e\u6995\u751f\u9662\u58eb\u5408\u4f5c\uff0c\u5728\u56fd\u9645\u5b66\u672f\u671f\u520aBiomass and Bioenergy (Q1; Impact factor: 5.8)\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u5173\u4e8e\u5229\u7528\u673a\u68b0\u5316\u5b66\u9884\u5904\u7406\u540c\u65f6\u751f\u4ea7\u9ad8\u7eaf\u5ea6\u7cd6\u548c\u9ad8\u6d53\u5ea6\u6728\u8d28\u7d20\u7684\u7814\u7a76\u6027\u8bba\u6587\u3002<\/p>\n

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\u7ed3\u679c\u53d1\u8868\u5728Biomass and Bioenergy\uff1a<\/p>\n

L Wang, J-Y Chen, Y Cao, Roger, Ruan, Zhen Fang*<\/strong>, Simultaneous production of high-concentration sugar and purity lignin from wheat straw via ball-milling assisted DES pretreatment for high-loading enzymatic hydrolysis. Biomass and Bioenergy 2026, 215, 109655. https:\/\/doi.org\/10.1016\/j.biombioe.2026.109655.<\/p>\n","protected":false},"excerpt":{"rendered":"

Simultaneous production of high-concentration sugar and […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/posts\/6434"}],"collection":[{"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/comments?post=6434"}],"version-history":[{"count":1,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/posts\/6434\/revisions"}],"predecessor-version":[{"id":6436,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/posts\/6434\/revisions\/6436"}],"wp:attachment":[{"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/media?parent=6434"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/categories?post=6434"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/tags?post=6434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}