{"id":167,"date":"2010-06-02T21:58:19","date_gmt":"2010-06-02T13:58:19","guid":{"rendered":"http:\/\/brg.groups.xtbg.ac.cn\/%e8%81%94%e7%b3%bb%e6%88%91%e4%bb%ac-8"},"modified":"2021-01-10T18:22:53","modified_gmt":"2021-01-10T10:22:53","slug":"%e8%81%94%e7%b3%bb%e6%88%91%e4%bb%ac-8","status":"publish","type":"page","link":"https:\/\/woodrefinery.com\/zhenfang\/%e8%81%94%e7%b3%bb%e6%88%91%e4%bb%ac-8\/","title":{"rendered":"Tech Transfer"},"content":{"rendered":"

1. Fast hydrolysis process \u5feb\u901f\u6c34\u89e3\u6728\u8d28\u7ea4\u7ef4\u7d20\u6280\u672f <\/strong>(US patent#: 8268126, 2012; US patent#: 9115215, 2015; US patent#: 9243303, 2016; Chinese patents: ZL200710141265.3, 2013; ZL201010297515.4, 2012)\u4e13\u5229\u8f6c\u8ba9\uff1a<\/p>\n

Lignocellulosic biomass (wood, grass) is completely solubilized in hot water to become \u201cwood solution\u201d that is subsequently hydrolyzed to sugars in seconds for biofuel production.<\/p>\n

I (Prof. Fang)\u00a0am the inventor of \u201cfast hydrolysis\u201d process (U.S. patent #: 8268126<\/strong><\/a>) entitled “Method, equipment and applications for fast complete dissolution and hydrolysis of lignocellulosic biomass”.\u00a0 The patent was issued on September 18, 2012 for technology that provides a simple and low-cost method to fast, completely and continuously dissolve and hydrolyze lignocellulosic biomass with great potential for a novel biorefinery.<\/p>\n

Briefly stated, my invention comprises method, equipment and applications for fast complete dissolution and hydrolysis of lignocellulosic biomass continuously.\u00a0 The unique features of my invention are simple<\/strong>, complete, continuous and fast dissolution and hydrolysis of actual<\/strong> lignocellulosic biomass (wood or grass)<\/strong>.\u00a0The advantages of my invention offer\u00a0a\u00a0simple, fast and low-cost\u00a0way of applying it on a large\u00a0commercial scale because of the unique features of the invention.<\/p>\n

I have 23 years experiences in bioenergy research at top universities and institutes around the world.\u00a0In my previous work, I found for the first time that cellulose could be completely dissolved in water at temperature above 320 o<\/sup>C and became a \u2018cellulose solution\u2019, which made it possible to build up a continuous flow reactor for the rapid hydrolysis of cellulose. However, the separating of pure cellulose from actual biomass (e.g., wood) is complicated and costly. It is difficult for the solubilization and hydrolysis of pure cellulose to be commercialized. Thus, I invented a \u2018fast hydrolysis\u2019 process of actual lignocellulosic biomass (wood) by adding 0.8 wt% Na2<\/sub>CO3<\/sub>, actual wood without pretreatment can be completely dissolved upon fast-heating (7~16\u00b0C\/s) to form a \u2018wood solution\u2019 at 329-367 o<\/sup>C at short reaction times (0.7-2 s). The \u2018wood solution\u2019 can be rapidly (ca. 15 s) hydrolyzed to sugars\/sugar oligomers under homogeneous conditions. The patent is the latest development in my 23-year effort in the study of biomass hydrolysis process, aimed at a simple, fast and low-cost method for a novel biorefinery. The \u2018fast hydrolysis\u2019 process will be the technological key to economic utilization of abundant lignocellulosic biomass as viable feedstocks for the production of industrial sugar, ethanol and chemicals. My pioneering work opens the door, for the first time, to the possibility of developing industrial-scale technology at competitive cost for producing biofuels and value-added products from lignocellulosic biomass based on the \u2018fast hydrolysis\u2019 process in a flow reactor.<\/p>\n

You may also visit the web for more detailed information about the: \u00a0U.S. patent #: 8268126<\/strong><\/a>. I am seeking to sell or license the patent rights, or other forms of collaboration to commercialize it. If you are potentially interested in the U.S. patent #: 8268126. Please contact me anytime at Tel: 86-25-58606657; E-mail: 483709907@qq.com; zhenfangATnjau.edu.cn; cf74ATnyu.edu<\/a>.<\/p>\n

\u5feb\u901f\u6c34\u89e3\u6728\u8d28\u7ea4\u7ef4\u7d20\u6280\u672f<\/strong>(US patent#: 8268126, 2012; US patent#: 9115215, 2015; US patent#: 9243303, 2016; Chinese patents: ZL200710141265.3, 2013; ZL201010297515.4, 2012)\u4e13\u5229\u8f6c\u8ba9\uff1a<\/p>\n

\u65b9\u771f\u6559\u6388\u53d1\u660e\uff1a\u4e0d\u7ecf\u4efb\u4f55\u9884\u5904\u7406\uff08\u8282\u80fd\uff09\uff0c\u52a0\u5fae\u91cf\u7684\u78b1\uff08\u73af\u4fdd\uff09\uff0c\u53ea\u9700\u77ed\u77ed\u51e0\u79d2\u949f\uff08\u5feb\u901f\uff09\uff0c100 %\u7684\u6728\u8d28\u7ea4\u7ef4\u7d20\uff08\u6728\u6750\u6216\u8349\uff09\u53ef\u4ee5\u5feb\u901f\u5b8c\u5168\u6eb6\u89e3\u4e8e\u6c34\u4e2d\uff0c\u8fd9\u6837\u6728\u8d28\u7ea4\u7ef4\u7d20\u6eb6\u6db2\u8c61\u6db2\u4f53\u77f3\u6cb9\u4e00\u6837\u5f88\u6613\u52a0\u5de5\uff0c\u5982\u5feb\u901f\u6c34\u89e3\u4e8e\u9ad8\u538b\u70ed\u6c34\u5f53\u4e2d\u3002\u9996\u5148\uff0c\u5f53\u6728\u8d28\u7ea4\u7ef4\u7d20\u9897\u7c92\u548c\u6c34\u5feb\u901f\u52a0\u70ed\u65f6\uff0c\u6728\u8d28\u7ea4\u7ef4\u7d20\u5feb\u901f\u5b8c\u5168\u6eb6\u89e3\uff0c\u968f\u540e\u7acb\u5373\u5728\u9ad8\u538b\u70ed\u6c34\u4e2d\u6c34\u89e3\u6210\u7cd6\u7c7b\u3002\u65b9\u771f\u7814\u7a76\u5458\u53d1\u660e\u5e76\u5efa\u7acb\u4e86\u4e00\u5957\u53ef\u64cd\u7eb5\u8fde\u7eed\u5316\u6c34\u89e3\u88c5\u7f6e\uff0c\u53ef\u5feb\u901f\u3001\u8fde\u7eed\u3001\u5927\u89c4\u6a21\u5730\u6c34\u89e3\u6728\u6750\u6765\u751f\u4ea7\u7cd6\u7c7b\uff0c\u4ece\u800c\u4f7f\u5b9e\u73b0\u5de5\u4e1a\u5316\u751f\u4ea7\u6210\u4e3a\u53ef\u80fd\u3002\u76f8\u5173\u7684\u7814\u7a76\u7533\u8bf7\u4e86\u4e13\u5229\uff1a<\/p>\n

(1)\u00a0<\/strong>ZL200710141265.3\uff1ahttp:\/\/www.google.com\/patents\/CN101235095B?cl=zh<\/a><\/p>\n

(2)\u00a0<\/strong>US patent#: 8268126\uff1ahttp:\/\/www.freepatentsonline.com\/8268126.html<\/a><\/p>\n

(3) \u00a0<\/strong>http:\/\/www.google.com\/patents\/CN101974161B?cl=zh<\/a><\/p>\n

\n

2. Synthesis of amides from lignocelluloses (\u4ee5\u6728\u8d28\u7ea4\u7ef4\u7d20\u4e3a\u539f\u6599\u5408\u6210\u9170\u80fa<\/span>):<\/strong> A\u00a0protocol is developed that shows in situ formed N-formyl quasi-catalytic species afford highly selective synthesis of formamides or amines with controllable levels from a variety of aldehyde- and ketone-derived platform chemical substrates (that can be easily produced via our patented \u201cfast hydrolysis\u201d process from lignocelluloses and subsequent catalytic conversions) under solvent-free conditions. Up to 99% yields of mono-substituted formamides are obtained in 3 min. The C-N bond formation and N-formyl species are prevalent in the cascade reaction sequence. Kinetic and isotope labeling experiments explicitly demonstrate that the C-N bond is activated for subsequent hydrogenation, in which formic acid acts as acid catalyst, hydrogen donor and as N-formyl species source that stabilize amine intermediates elucidated with density functional theory. The protocol provides access to imides from aldehydes, ketones, carboxylic acids, and mixed-substrates, requires no special catalysts, solvents or techniques and provides new avenues for amination chemistry. (Patent: PCT\/CN2019\/098614, 2019; Nature Communications, 10<\/strong>, 699, 2019, Green Chem,\u00a0https:\/\/doi.org\/10.1039\/C9GC03655E<\/a>, 2020<\/strong>).<\/p>\n

3. Magnetic solid catalyst for biodiesel production (<\/strong>\u4e00\u79cd\u7528\u4e8e\u751f\u7269\u67f4\u6cb9\u5236\u5907\u7684\u78b3\u57fa\u78c1\u6027\u56fa\u4f53\u50ac\u5316\u5242\u5408\u6210\u65b9\u6cd5) (Chinese patents: ZL201410764721.X, 2016; ZL201420785283.0, 2015; ZL201220038727.5, 2012; ZL201110334924.1, 2013).<\/span><\/p>\n

A cheap and high active magnetic heterogeneous catalyst (Na2<\/sub>SiO3<\/sub>@Fe3<\/sub>O4<\/sub>\/C) was prepared for the production of biodiesel from oils with high acid value (AV).<\/p>\n

With the catalyst and assisted by US, soybean biodiesel yield reached > 90% in only 20 min (or at 318 K) and 97.9% under the optimal conditions. It was easily magnetically separated for 5 cycles with 94.9% recovery rate and biodiesel yield > 80% with both US and MS. The catalyst transesterified Jatropha<\/em> oil with biodiesel yields of 94.7%, 93.2% and 83.5% at AV of 1.3, 4.8 and 7.3 (mg KOH\/g) with US, and was cycled 5 times with yield > 70% at AV of 4.8 assisted by US and MS. High biodiesel yield (90.7%) was still achieved from high AV oil (4.8) at low US energy density (0.1 W\/mL) and MS. The catalyst combined with US and MS can find practical application for direct production of biodiesel from oils with high AV.<\/p>\n

Magnetically recyclable catalysts are synthesized to produce biodiesel in a compacted flow reactor without discharging liquid catalyst wastes. Short reaction time is achieved by using microwave and ultrasound.<\/span><\/p>\n

(URL: <\/span>https:\/\/woodrefinery.com\/zhenfang\/biodiesel-is-synthesized-successfully-in-a-pilot-continuous-compacted-flow-reactor-3-5-tday-designed-by-biomass-group\/<\/span><\/a>, Patented reactor<\/strong> license transferred to Shandong Yikang pharmaceutical co. LTD on Oct. 23, 2018<\/span>).<\/span><\/p>\n

———————————————————<\/p>\n

4. One-step and low\/room temperature synthesis of liquid biofuels from carbohydrates (Patents: PCT\/CN2017\/106729, CN 106861754 A).\u00a0<\/span><\/span><\/strong><\/p>\n

Nanocatalysts were syntheisized\u00a0to catalyze the high yield production of liquid biofuels (e.g., methyl levulinate, \u03b3-valerolactone, 2,5-dimethylfuran, methylfuran) at low temperatures directly from carbohydrates (e.g., sugars, cellulose). It is found that 95% 2,5-dimethylfuran yield was obtained from fructose at 110 \u00b0C, 99% 2,5-dimethylfuran yield from 5-hydroxymethylfurfural and 97% 2-methylfuran yield from furfural were even achieved at room temperature (25 \u00b0C) when polymethylhydrosiloxane was used as H-donor. Therefore, liquid biofuels (e.g., 2,5-dimethylfuran) can be produced from sugars via<\/em> the hydrolysis of lignocellulosic biomass that is easy for commercial applications in simple and inexpensive reactors.
\n——————————————————————————————-<\/p>\n

\u5730\u5740\uff1a<\/strong>\u6c5f\u82cf\u5357\u4eac\u6d66\u53e3\u533a\u70b9\u5c06\u53f0\u5357\u4eac\u519c\u4e1a\u5927\u5b66\u5de5\u5b66\u9662\u751f\u7269\u80fd\u6e90\u7ec4<\/p>\n

\u90ae\u7f16\uff1a210031 <\/strong><\/p>\n

Tel: 86-25-58606657<\/p>\n

E-mail: 483709907@qq.com; zhenfangATnjau.edu.cn<\/p>\n","protected":false},"excerpt":{"rendered":"

1. Fast hydrolysis process \u5feb\u901f\u6c34\u89e3\u6728\u8d28\u7ea4\u7ef4\u7d20\u6280\u672f (US patent#: 826 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":7,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/pages\/167"}],"collection":[{"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/comments?post=167"}],"version-history":[{"count":6,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/pages\/167\/revisions"}],"predecessor-version":[{"id":4322,"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/pages\/167\/revisions\/4322"}],"wp:attachment":[{"href":"https:\/\/woodrefinery.com\/zhenfang\/wp-json\/wp\/v2\/media?parent=167"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}